Rat Macrophage Metalloelastase, MMP12 ELISA Kit, 96T Filtration The breast cancer susceptibility gene

The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q

May regulate the calcium Channel activity of TRPCs

and chondrocyte terminal differentiation

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family

The human genome contains a related pseudogene

Rat Macrophage Metalloelastase, MMP12 ELISA Kit, 96T Filtration The breast cancer susceptibility geneMay be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity).