TIS11B Polyclonal Antibody, 100ul Oligo Pool Overexpression of this gene suppresses

Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2)| which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades

GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity

The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins

GRK7 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family

Mutations in this gene are associated with achondrogenesis

TIS11B Polyclonal Antibody, 100ul Oligo Pool Overexpression of this gene suppressesZinc finger protein 36 C3H1 type like 1 encoded by ZFP36L1 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. Zinc finger protein 36 C3H1 type like 1 is activated by, and mediates the responses of many cell