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FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance This gene encodes a large

SKU: 82381542017

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FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance This gene encodes a largeFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.

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Description

This gene encodes a large protein that forms a structural component of the nuclear matrix

In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation

The protein that coordinates these activities is the basal transcription factor TFIID

formed between homologous chromosomes during meiotic prophase

The protein encoded by this gene is a core subunit of the elongator complex

FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance This gene encodes a largeFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.

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