p53 Polyclonal Antibody, 100ul[BT-AP06810] Purification The protein encoded by this

The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment

and an array of carcinoma cell lines

The protein encoded by this gene is a Rab-GTPase-activating protein| and contains two phopshotyrosine-binding domains (PTB1 and PTB2)| a calmodulin-binding domain (CBD)| a Rab-GTPase domain| and multiple AKT phosphomotifs

as indicated for members 1-3

This protein localizes to the extracellular matrix

p53 Polyclonal Antibody, 100ul[BT-AP06810] Purification The protein encoded by thisTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni