MAGA3 Polyclonal Antibody, 50ul Gene Synthesis It plays a negative regulatory

It plays a negative regulatory role in the Ras-Raf1-MAPK pathway| and knockout mice have been shown to develop spontaneous tumors| suggesting a role as a tumor suppressor gene

acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide

Mutations affecting CD40 are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3)

Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias

subunit:Interacts with SLIT2 and ENAH

MAGA3 Polyclonal Antibody, 50ul Gene Synthesis It plays a negative regulatoryThis gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some