HNF-4 Alpha/Gamma Polyclonal Antibody, 20ul[BT-AP04161] Centrifuge Tube (Bottle) This protein contains 7 transmembrane

This protein contains 7 transmembrane domains and conserved cysteine residues

The nuclear-encoded DNA pol γ is the only DNA polymerase required for the replication of the mitochondrial DNA

and it is abrogated by mutations in the pleckstrin homology domain of AKT1

This autosomal dominant disorder is characterized by abnormal water reabsorption by kidney tubules due

but it differs enough to possibly be considered as part of a new subfamily

HNF-4 Alpha/Gamma Polyclonal Antibody, 20ul[BT-AP04161] Centrifuge Tube (Bottle) This protein contains 7 transmembraneHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal