Lunatic Fringe Polyclonal Antibody, 20ul Peptide Modification Multiple transcript variants encoding different

Multiple transcript variants encoding different isoforms have been found for BSG

The encoded enzyme (carbohydrate sulfotransferase 2) catalyzes the sulfation of a nonreducing N-acetylglucosamine residue

The two variants are differentially expressed in embryonic tissues

CD58 encodes a member of the immunoglobulin superfamily

BMP6 (bone morphogenetic protein 6) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

Lunatic Fringe Polyclonal Antibody, 20ul Peptide Modification Multiple transcript variants encoding differentLFNG is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose specific beta 1,3 N acetylglucosaminyltransferase activity that leads to elongation of O linked fucose