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CD82 Polyclonal Antibody, 100ul Cell Dissociation the NURF complex

SKU: 85491973370

4.4
EUR123.75 EUR148.75

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CD82 Polyclonal Antibody, 100ul Cell Dissociation the NURF complexThis metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate

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Description

the NURF complex

This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box

Defects in this gene are a cause of Peters-plus syndrome (PPS)

but lacks cytoplasmic domain

Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles

CD82 Polyclonal Antibody, 100ul Cell Dissociation the NURF complexThis metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate

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