SETBP Rabbit Polyclonal Antibody, 20ul Immunology preventing premature release of meiosis-specific

preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres

Different members of the subfamily can readily form heterodimers

The encoded protein (nuclear cap binding protein subunit 2) has an RNP domain commonly found in RNA binding proteins

This protein participates in the signal transduction of CD40

Pseudogenes are present on chromosomes 5 and 22

SETBP Rabbit Polyclonal Antibody, 20ul Immunology preventing premature release of meiosis-specificThis gene encodes a protein which contains a several motifs including a ski homology region and a SET binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.