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Histone H2A Polyclonal Antibody, 100ul[BT-AP03999] Nucleic Acid Isolation & Purification Like other ABC transmembrane transporter

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Histone H2A Polyclonal Antibody, 100ul[BT-AP03999] Nucleic Acid Isolation & Purification Like other ABC transmembrane transporterHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.

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Description

Like other ABC transmembrane transporter proteins

This gene encodes a protein that appears to belong to a family of evolutionarily related proteins (DUF78)

Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes

This gene encodes a protein containing three zinc finger domains and a nuclear localization signal

A second transcript variant has been described| but its full length nature has not been determined

Histone H2A Polyclonal Antibody, 100ul[BT-AP03999] Nucleic Acid Isolation & Purification Like other ABC transmembrane transporterHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.

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