ZAP-70(Phospho Tyr493) Polyclonal Antibody, 50ul Endonucleases & Exonucleases The transmembrane protein encoded by

The transmembrane protein encoded by this gene (interleukin 17A receptor

and p53-mediated effects on growth

This protein forms homo- or hetero-dimers with other Ikaros family members

Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4

Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity

ZAP-70(Phospho Tyr493) Polyclonal Antibody, 50ul Endonucleases & Exonucleases The transmembrane protein encoded byThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T cell antigen receptor (TCR) stimulation, functions in the initial step of TCR mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene