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PDLIM5(Phospho Tyr251) Polyclonal Antibody, 100ul Endonucleases & Exonucleases May also regulate ESR1 levels

SKU: 87182145883

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PDLIM5(Phospho Tyr251) Polyclonal Antibody, 100ul Endonucleases & Exonucleases May also regulate ESR1 levelsThis gene encodes a member of a family of proteins that possess a 100 amino acid PDZ domain at the N terminus and one to three LIM domains at the C terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript

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Description

May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT

inflamation

It is present in the plasma membrane and intracellular vesicles

DNA repair protein XRCC1 encoded by XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents

FST317 and FST344 containing 317 and 344 amino acids respectively

PDLIM5(Phospho Tyr251) Polyclonal Antibody, 100ul Endonucleases & Exonucleases May also regulate ESR1 levelsThis gene encodes a member of a family of proteins that possess a 100 amino acid PDZ domain at the N terminus and one to three LIM domains at the C terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript

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