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Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing Following cleavage| the mature protein

SKU: 87252243449

4.1
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Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing Following cleavage| the mature proteinThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

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Description

Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

Unleash the power of recombinant trypsin solution

Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis

Component of the little elongation complex (LEC)

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation

Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing Following cleavage| the mature proteinThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

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