NF-YC Polyclonal Antibody, 100ul Sealing Film It functions as histone acetyltransferase

It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation

Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion

and is therefore a potential candidate gene for this disorder

Alternatively spliced transcript variants encoding multiple isoforms have been observed for MED27

Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome

NF-YC Polyclonal Antibody, 100ul Sealing Film It functions as histone acetyltransferaseNFYC encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone like motif. Multiple transcript variants