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Caspase-1 Polyclonal Antibody, 50ul[BT-AP01192] Reservoirs The protein binds both insulin-like

SKU: 87805690644

4.7
SEK162.00 SEK196.00

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Caspase-1 Polyclonal Antibody, 50ul[BT-AP01192] Reservoirs The protein binds both insulin-likeCASP1 (caspase 1) encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP1 was identified by its ability to proteolytically

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Description

The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms

Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS)

Additionally| this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer

this protein does not interact with RASGAP

through G-protein coupled receptor stimulation

Caspase-1 Polyclonal Antibody, 50ul[BT-AP01192] Reservoirs The protein binds both insulin-likeCASP1 (caspase 1) encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP1 was identified by its ability to proteolytically

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