Arkadia Polyclonal Antibody, 20ul Gene Editing Transcripts at this locus may

Transcripts at this locus may also undergo A to I editing

Members of the family share several distinct protein modules

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Humanized functional design

Arkadia Polyclonal Antibody, 20ul Gene Editing Transcripts at this locus mayThe protein encoded by RNF111 (ring finger protein 111) is a nuclear RING domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) beta NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF beta target gene transcription. As a modulator of the nodal signaling cascade, RNF111 plays a critical role in the