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MLH3 Polyclonal Antibody, 50ul Modified Oligos Diseases associated with ELOVL2 include

SKU: 88546119035

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MLH3 Polyclonal Antibody, 50ul Modified Oligos Diseases associated with ELOVL2 includeMLH3 is a member of the MutL homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The mutL homolog 3 encoded by MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis

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Description

Diseases associated with ELOVL2 include gastric antral vascular ectasia and malignant melanoma

in which it interacts directly with SKP1

Important for the resorption of phosphate by the kidney

this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release

This protein preferentially binds to the SH3 domain of c-Abl kinase

MLH3 Polyclonal Antibody, 50ul Modified Oligos Diseases associated with ELOVL2 includeMLH3 is a member of the MutL homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The mutL homolog 3 encoded by MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis

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