FASTKD2 Polyclonal Antibody, 50ul PCR Series Mutations in BRCA1 are responsible

Mutations in BRCA1 are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers

This gene encodes a protein containing a Kruppel-associated box domain and multiple zinc finger domains

is essential for heart development

The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer

SUBCELLULAR LOCATION: cell membrane

FASTKD2 Polyclonal Antibody, 50ul PCR Series Mutations in BRCA1 are responsibleFASTKD2 encodes FAST kinase domain containing protein 2 that is localized in the mitochondrial inner compartment and that may play a role in mitochondrial apoptosis. Nonsense mutations have been reported to result in cytochrome c oxidase deficiency.