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YAP(Phospho-Ser109) Rabbit Polyclonal Antibody, 100ul Immuno Plates making it a valuable asset

SKU: 89259207531

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YAP(Phospho-Ser109) Rabbit Polyclonal Antibody, 100ul Immuno Plates making it a valuable assetThis gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development growth repair and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

making it a valuable asset in any laboratory

This gene encodes multiple protein isoforms that differ in their inhibitory activity

CRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion

SLC39A1 encodes a member of the zinc-iron permease family

this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion

YAP(Phospho-Ser109) Rabbit Polyclonal Antibody, 100ul Immuno Plates making it a valuable assetThis gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development growth repair and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

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