SIRT1(Phospho-Ser549) Rabbit Polyclonal Antibody, 20ul Live Cell Imaging The protein encoded by ACO1

The protein encoded by ACO1 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions

These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs

It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling

Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome

Contains 1 MAGE domain

SIRT1(Phospho-Ser549) Rabbit Polyclonal Antibody, 20ul Live Cell Imaging The protein encoded by ACO1This gene encodes a member of the sirtuin family of proteins homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular