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TRPS1 Polyclonal Antibody, 50ul Pipette Controller The encoded protein may bind

SKU: 89613170183

4.1
USD162.00 USD210.00

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TRPS1 Polyclonal Antibody, 50ul Pipette Controller The encoded protein may bindTRPS1 (transcriptional repressor GATA binding 1) encodes a transcription factor that represses GATA regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in TRPS1 are a cause of tricho rhino phalangeal syndrome (TRPS) types I III.

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Description

The encoded protein may bind copper

GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity

The encoded protein is an endogenous substrate for protein kinase C

and wound healing

It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor| alpha)| targeting it for degradation and thus activating nuclear factor kappa-B

TRPS1 Polyclonal Antibody, 50ul Pipette Controller The encoded protein may bindTRPS1 (transcriptional repressor GATA binding 1) encodes a transcription factor that represses GATA regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in TRPS1 are a cause of tricho rhino phalangeal syndrome (TRPS) types I III.

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