APOA Rabbit Polyclonal Antibody, 50ul Immunology Knockout studies in mice suggest

Knockout studies in mice suggest that this gene plays a role in T-helper cell activation

Interferons are small regulatory molecules that function in cell signaling in response to viruses and other pathogens or tumor cells

It is noteworthy that this gene and LEPROT gene (GeneID: 54741) share the same promoter and the first 2 exons

although the ratio of 1 to 2 increases by term

It has tyrosine kinase activity

APOA Rabbit Polyclonal Antibody, 50ul Immunology Knockout studies in mice suggestThe protein encoded by this gene is a serine proteinase that inhibits the activity of tissue type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual the encoded protein contains 2 43 copies