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Hel-N1 Polyclonal Antibody, 50ul Sampling Tubes 118A>G allele has been associated

SKU: 90793054708

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Hel-N1 Polyclonal Antibody, 50ul Sampling Tubes 118A>G allele has been associatedELAV like protein 2 encoded by ELAVL2 is a neural specific RNA binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. ELAV like protein 2 may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting

IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family

DUSP7 belongs to a class of DUSPs| designated MKPs| that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795)| JNK (see MIM 601158)| and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins

and the skeletal muscle isoform is encoded by PHKA1 (phosphorylase kinase regulatory subunit alpha 1)

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family

Hel-N1 Polyclonal Antibody, 50ul Sampling Tubes 118A>G allele has been associatedELAV like protein 2 encoded by ELAVL2 is a neural specific RNA binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. ELAV like protein 2 may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene.

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