CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries It is also found to

It is also found to be expressed in lipogenic breast cancers| which suggests a role in controlling tumor lipid metabolism

the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation

The gene encodes a member of the integrin alpha chain family of proteins

HMGB1 encodes a protein that belongs to the High Mobility Group-box superfamily

EPHB6 encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins

CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries It is also found toThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.