NFkB p65 Monoclonal Antibody(5G6), 100ul sgRNA Library Construction Studies of the rat homolog

Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection

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Interacts with HEXIM1 and MAP1S

Mutations in HSD11B1 and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency

NFkB p65 Monoclonal Antibody(5G6), 100ul sgRNA Library Construction Studies of the rat homologNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four