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E2F-6 Polyclonal Antibody, 20ul Drying & Desiccation ADGRE1 encodes adhesion G protein-coupled

SKU: 95384273128

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E2F-6 Polyclonal Antibody, 20ul Drying & Desiccation ADGRE1 encodes adhesion G protein-coupledE2F6 encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. E2F transcription factor 6 encoded by E2F6 lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene

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Description

ADGRE1 encodes adhesion G protein-coupled receptor E1 that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus

It is an integral membrane protein functioning as a receptor

The cyclin dependent kinase 7 encoded by CDK7 is a member of the cyclin-dependent protein kinase (CDK) family

and plays an important role in transcriptional regulation

The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling

E2F-6 Polyclonal Antibody, 20ul Drying & Desiccation ADGRE1 encodes adhesion G protein-coupledE2F6 encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. E2F transcription factor 6 encoded by E2F6 lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene

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