CHST5 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Mutations in this gene are

Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome

Cytochrome c oxidase I (COX1) also known as mitochondrially encoded cytochrome c oxidase I (MT-CO1) is a protein that in humans is encoded by the MT-CO1 gene

Unlike the rat homolog| the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements

This gene is a member of a conserved family of genes that share a common DNA-binding domain

This protein interacts with the transforming growth factor (TGF)-beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators

CHST5 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Mutations in this gene areThe protein encoded by this gene belongs to the Gal GalNAc GlcNAc 6 O sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N acetylgalactosamine (GalNAc), or N acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O linked sugars of mucin type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in