CD70 Polyclonal Antibody, 20ul[BT-AP07445] Bio-Reaction Tube This locus encodes a LEM

This locus encodes a LEM domain-containing protein

The protein encoded by this gene binds to and is inhibited by dihydropyridine

There is a combination of at least four alternatively spliced domains| two extracellular (X1 and X2) and two cytoplasmic (A and B)

The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2

Among its related pathways are Gene Expression and Cell Cycle

CD70 Polyclonal Antibody, 20ul[BT-AP07445] Bio-Reaction Tube This locus encodes a LEMThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27 CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B cell activation,