MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix an essential protein required to

an essential protein required to the initiation of DNA replication

transcription regulation

Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis

The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation

This gene encodes a member of the class-II aminoacyl-tRNA synthetase family

MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix an essential protein required toMucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007