TLE3 Rabbit Polyclonal Antibody, 100ul Insect Expression The deletion of one copy

The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome

The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions

which binds to pituitary tumor-transforming 1 protein (PTTG1)

The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis

PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth| differentiation| mitotic cycle| and oncogenic transformation

TLE3 Rabbit Polyclonal Antibody, 100ul Insect Expression The deletion of one copyThis gene encodes a transcriptional co repressor protein that belongs to the transducin like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional