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HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix This protein may play a

SKU: 97045001773

4.6
SEK123.75 SEK172.75

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HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix This protein may play aHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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Description

This protein may play a role in physiologic functions at mucosal sites

A serine-rich region promotes activation of the serum response element (SRE)

The coding region of this gene is intronless

PARPs can also function as transcriptional cofactors (Yu et al

Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients

HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix This protein may play aHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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