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Although chemotherapy is mainly used in patients with metastatic disease, the treatment of advanced CCS remains challenging due to the lack of an established standard treatment system

When there is too much oxalate and not enough liquid to dilute it in the urine, it binds with calcium in the kidneys to form crystals

Bravo-Vzquez LA, Paul S, Coln-Jurado MG et al (2024) Exploring the therapeutic significance of microRNAs and lncRNAs in kidney diseases

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In addition, prior research indicated that carbohydrates, sugar alcohols, bile acids, carboxylic acids, and secondary bile acids were able to influence the colonization of commensals in the digestive system [28]