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StARD13 Polyclonal Antibody, 50ul Electronic Pipette The longest gene product (isoform

SKU: 97992695803

4.0
EUR162.00 EUR185.00

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StARD13 Polyclonal Antibody, 50ul Electronic Pipette The longest gene product (isoformSTARD13 (StAR related lipid transfer domain containing 13) encodes a protein which contains an N terminal sterile alpha motif (SAM) for protein protein interactions, followed by an ATP GTP binding motif, a GTPase activating protein (GAP) domain, and a C terminal STAR related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma

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Description

The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing

The Fas associated via death domain encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals

High tensile strength

Involved in protein trafficking

A dominant negative mutant of RNF14 has been demonstrated to inhibit the AR-mediated growth of prostate cancer

StARD13 Polyclonal Antibody, 50ul Electronic Pipette The longest gene product (isoformSTARD13 (StAR related lipid transfer domain containing 13) encodes a protein which contains an N terminal sterile alpha motif (SAM) for protein protein interactions, followed by an ATP GTP binding motif, a GTPase activating protein (GAP) domain, and a C terminal STAR related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma

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