CD275 Polyclonal Antibody, 100ul sgRNA Library Construction DFF45/ICAD has been identified as

DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD

Expression of this gene may play a role in breast cancer

required for differentiation of bone marrow stromal cells

instigated by a number of factors including calcium ion and cAMP levels

A dominant negative mutant of RNF14 has been demonstrated to inhibit the AR-mediated growth of prostate cancer

CD275 Polyclonal Antibody, 100ul sgRNA Library Construction DFF45/ICAD has been identified asalternative products: Additional isoforms seem to exist,Ligand for the T cell specific cell surface receptor ICOS. Acts as a costimulatory signal for T cell proliferation and cytokine secretion; induces also B cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co stimulating memory T cell