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BMP-4 Rabbit Polyclonal Antibody, 20ul Antibody Humanization APM2 gene is exclusively expressed

SKU: 99045134100

4.4
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BMP-4 Rabbit Polyclonal Antibody, 20ul Antibody Humanization APM2 gene is exclusively expresseddisease: Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6)

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Description

APM2 gene is exclusively expressed in adipose tissue

This gene encodes three main isoforms that differ in activities and subcellular location

The mannose receptor C type 2 plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands

When expressed in cells| this protein activated NF-kappaB and induced the phosphorylation of BCL10

It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1)

BMP-4 Rabbit Polyclonal Antibody, 20ul Antibody Humanization APM2 gene is exclusively expresseddisease: Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6)

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