DOC11 Polyclonal Antibody, 50ul Cryogenic Vials Vora (1981) [PubMed 6451249] determined

Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4

It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene

The protein encoded by BAG4 is a member of the BAG1-related protein family

This gene is a homolog of the Drosophila delta gene

The gene of VN1R4 maps to chromosome 19q13

DOC11 Polyclonal Antibody, 50ul Cryogenic Vials Vora (1981) [PubMed 6451249] determinedThe DHR 2 domain is necessary for the GEF activity.,Guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR 1 (CZH 1) domain.,Contains 1 DHR 2 (CZH 2) domain.,Contains 1 PH domain.,subunit: Interacts with CDC42.,