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In these cases, the real issue is inflammation, which not only affects the muscles but can also lead to secondary injury mechanisms within the muscles themselves

The combination of IDE1, CHIR, and LY294002 (a PI3K inhibitor) induced DE specification from human umbilical cord-derived mesenchymal stem cells (Luo et al., 2021)

Numerous studies have suggested that sphingolipid metabolites function as key regulators in the T-cell lineage specification and immune responses in inflammatory diseases (5861, 63), including MS and EAE (56, 57, 62, 64)

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