CHD2 Polyclonal Antibody, 20ul Vacuum Filter There is a related pseudogene

There is a related pseudogene located immediately adjacent to this locus

This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators

The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR

tissue specificity:Expressed in a broad range of tissues

which maps to chromosome 10p

CHD2 Polyclonal Antibody, 20ul Vacuum Filter There is a related pseudogeneThe CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2 related helicase ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.