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FYCO1 Polyclonal Antibody, 50ul Modified Oligos Specific instances of aberrant gene

SKU: 99401886979

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PLN162.00 PLN183.00

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FYCO1 Polyclonal Antibody, 50ul Modified Oligos Specific instances of aberrant geneThis gene encodes a protein that contains a RUN domain, FYVE type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol 3 phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract 2 (CATC2).

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Description

Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL)

This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen| which is required for the final step in the synthesis of soluble A and B antigens

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thus is potentially associated with higher risk of breast cancer

FYCO1 Polyclonal Antibody, 50ul Modified Oligos Specific instances of aberrant geneThis gene encodes a protein that contains a RUN domain, FYVE type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol 3 phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract 2 (CATC2).

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