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Based on the above studies, we hypothesized that the pathogenic oral bacterias established by the periodontitis mentioned above might cause the release of cytokines by immune cells in the blood, thereby causing kidney damage

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In addition, chronic stimulation of VANs reduces food intake and weight gain in rats 45,46,47 and is associated with weight loss in humans 48 , highlighting the long-term physiological relevance of vagal signaling

These results underscore Semaglutides potential as a powerful tool in obesity management