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Due to their weekly dosing schedule and greater mean weight loss seen in trials (15% for semaglutide and 21% for tirzepatide, compared to 8% with liraglutide), semaglutide and tirzepatide are more frequently prescribed than liraglutide for treatment of obesity [33,34,35]

Although this can support weight loss goals, significant reductions in calorie intake can sometimes affect reproductive hormone production

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