TAK-242 Catalog No.:M10780-10 Chemical Name: methyl 4-(6-amino-9H-purin-9-yl)-2-hydroxybutanoate

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TAK-242 Catalog No.:M10780-10 Chemical Name: methyl 4-(6-amino-9H-purin-9-yl)-2-hydroxybutanoateResatorvid, also known as TAK 242, is a cell permeable inhibitor of TLR4 signaling, blocking LPS induced production of NO, TNF , IL 6, and IL 1 in macrophages with IC50 values of 1 11 nM. Resatorvid binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules. Resatorvid provides neuroprotection in experimental traumatic brain injury: implication in the treatment of human brain injury. Product information CAS

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