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ID-8 - DYRK Inhibitor. CAS# 147591-46-6 0228 Smiles: CC1=C(C=CC=C1C)NC1=CC(Cl)=NC(=N1)SCC(O)=O

ID-8 - DYRK Inhibitor. CAS# 147591-46-6 0228 Smiles: CC1=C(C=CC=C1C)NC1=CC(Cl)=NC(=N1)SCC(O)=O

Name: ID-8 - DYRK Inhibitor. CAS# 147591-46-6 0228 Smiles: CC1=C(C=CC=C1C)NC1=CC(Cl)=NC(=N1)SCC(O)=O
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ID-8 - DYRK Inhibitor. CAS# 147591-46-6 0228 Smiles: CC1=C(C=CC=C1C)NC1=CC(Cl)=NC(=N1)SCC(O)=OID 8, CAS No. 147591 46 6, is a highly potent and selective small molecule inhibitor of dual specificity tyrosine phosphorylation regulated kinase (DYRK). It could support Wnt induced human embryonic stem cell proliferation and survival without differentiation. Using ID 8, a novel and simple chemically defined xeno free culture system was developed that allows for long term expansion of human pluripotent stem cells without FGF or TGF beta pathway

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Description

Smiles: CC1=C(C=CC=C1C)NC1=CC(Cl)=NC(=N1)SCC(O)=O

6-dimethyl-2-oxo-1

4 μM for KDM4A and 9

It can Induce glucose-dependent insulin secretion in pancreatic MIN6 cells and in vivo

CAS Number: 1346574-57-9

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