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Sal003 55283 It is highly selective for

SKU: 15545483751

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PLN85.00 PLN135.00

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Sal003 55283 It is highly selective forSAL 003 is a cell permeable inhibitor of eIF2 dephosphorylation. SAL003 is an Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Sal003mediated upregulation of eIF2 phosphorylation suppressed cisplatininduced p53 activation. Furthermore, reduction of eIF2 phosphorylation by PERK knockdown enhanced cisplatin induced p53 activation and apoptosis. Product information CAS Number: 1164470 53 4 Molecular Weight: 463. 21 Formula:

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Description

It is highly selective for the H1 receptor and does not cross the blood-brain-barrier

PubMed PMID: 25296383

Steegmaier M

Chemical Name: (2S)-3-(3

CAS Number: 361442-04-8

Sal003 55283 It is highly selective forSAL 003 is a cell permeable inhibitor of eIF2 dephosphorylation. SAL003 is an Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Sal003mediated upregulation of eIF2 phosphorylation suppressed cisplatininduced p53 activation. Furthermore, reduction of eIF2 phosphorylation by PERK knockdown enhanced cisplatin induced p53 activation and apoptosis. Product information CAS Number: 1164470 53 4 Molecular Weight: 463. 21 Formula:

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