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doi: 10.3390/ijms21217870 159

Funding This study was funded by the Spanish Ministry of Economy and Competitiveness (AGL2017-89017-R and PID2021-126988OB-I00)

(2015) 10:e0125361

Measuring an estradiol and FSH/LH are helpful to determine menopausal status, prolactin (to look for a prolactinoma and 17-OH progesterone (to look for congenital adrenal hyperplasia (CAH) are helpful to exclude other diseases that give menstrual abnormalities

Discontinuation of bromocriptine therapy has been shown to lead to recurrence of hyperprolactinemia in most patients and to tumour regrowth if treatment duration has been less than 2 years.18 Passos and associates18 reported maintenance of normal prolactin levels and absence of adenoma re-expansion after withdrawal of dopamine agonist therapy in 6.6% to 37.5% of patients