(R)-5-Hydroxymethyl Tolterodine Size:Solid 2 mg 1448297-52-6
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(R)-5-Hydroxymethyl Tolterodine Size:Solid 2 mg 1448297-52-6Desfesoterodine, also known as PNU 200577, is a major pharmacologically active metabolite of tolterodine, a new muscarinic receptor antagonist intended for the treatment of an overactive bladder. In vitro, PNU 200577 produced a competitive and concentration dependent inhibition of carbachol induced contraction of guinea pig isolated urinary bladder strips (KB = 0. 84 nM; pA2 = 9. 14). In vivo, PNU 200577 was significantly more potent at inhibiting
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