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VCP 171 Size:2mg solid 5]decan-1-one

SKU: 26459445034

4.1
SEK162.00 SEK206.00

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VCP 171 Size:2mg solid 5]decan-1-oneAdenosine A1 receptor positive allosteric modulator (PAM) (pKB = 5. 65, binding cooperativity with NECA 0. 68). In absence of orthosteric agonist, VCP171 behaves as an allosteric partial agonist, inhibiting cAMP activity. Inhibits AMPA receptor mediated evoked excitatory postsynaptic current (eEPSC) amplitude in lamina I and II neurons in a rat partial nerve injury model of neuropathic pain. Product information CAS Number: 1018830 99 3 Molecular

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Description

5]decan-1-one

Degradation Inducing Moiety A

61(9):797-805

reduces HIF-1α

NIBR3049 shows moderate activity in this cellular assay (IC50=689 nM

VCP 171 Size:2mg solid 5]decan-1-oneAdenosine A1 receptor positive allosteric modulator (PAM) (pKB = 5. 65, binding cooperativity with NECA 0. 68). In absence of orthosteric agonist, VCP171 behaves as an allosteric partial agonist, inhibiting cAMP activity. Inhibits AMPA receptor mediated evoked excitatory postsynaptic current (eEPSC) amplitude in lamina I and II neurons in a rat partial nerve injury model of neuropathic pain. Product information CAS Number: 1018830 99 3 Molecular

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