ELR510444 - CAS# 1233948-35-0 size:10mg solid For the related AGC kinases
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ELR510444 - CAS# 1233948-35-0 size:10mg solid For the related AGC kinasesELR510444, CAS No. 1233948 35 0, is a potent microtube disruptor with potential anticancer activity. ELR510444 has potent microtubule disrupting activity, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells. ELR510444 potently inhibited cell proliferation with an IC(50) value of 30. 9 nM in MDA MB 231 cells, inhibited the rate and extent of purified tubulin
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