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TRCP6-IN-1 Size:Solid 2 mg Treatment of growing AML cells

SKU: 2804998012

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TRCP6-IN-1 Size:Solid 2 mg Treatment of growing AML cellsSAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7 mediated Ca(2+) influx into cells with IC50 s of 9. 5, 282 and 226 nM, whereas TRPC4 and TRPC5 mediated Ca(2+) entry was not affected. Product information CAS Number: 1333210 07 3 Molecular Weight: 367. 87 Formula: C21H22ClN3O Chemical Name: 4

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Description

Treatment of growing AML cells with RO-3306 induced G2/M-phase cell cycle arrest and apoptosis in a dose- and time-dependent manner

BSJ-03-204 (1 μM

Formula: C7H14O6

334(6061):1372-7

InChiKey: ZJOKWAWPAPMNIM-UHFFFAOYSA-N

TRCP6-IN-1 Size:Solid 2 mg Treatment of growing AML cellsSAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7 mediated Ca(2+) influx into cells with IC50 s of 9. 5, 282 and 226 nM, whereas TRPC4 and TRPC5 mediated Ca(2+) entry was not affected. Product information CAS Number: 1333210 07 3 Molecular Weight: 367. 87 Formula: C21H22ClN3O Chemical Name: 4

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