SORT Polyclonal Antibody, 20ul Human Genome Knockout Libraries Defects in EP300 are a

Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein

CD2BP2 encodes a bi-functional protein (CD2 cytoplasmic tail binding protein 2)

CDKN2B lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors

Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged

SORT Polyclonal Antibody, 20ul Human Genome Knockout Libraries Defects in EP300 are aThis gene encodes a member of the VPS10 related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing